Orlistat is an extremely efficient drug that blocks and prevents the absorption of fat by the body. Created by Swiss group of scientists, the efficiency is achieved mainly through the production of an enzyme that breaks down fat. Orlistat effect is based on the cleavage of the enzyme. Therefore, the organism only digested proteins, carbohydrates and vitamins from the food that enters the human body, while all the unprocessed fats found naturally.
Orlistat pharmacological action
This simple and very effective method leads to the fact that the body starts to work with its reserves. As a result, within the short period of time it leads to the weight reduction. But the drug is allowed to be accepted only for patients suffering from obesity.
The medication demonstrated impressive effectiveness in combination with antidiabetic drugs, as very often, diabetes and obesity are inseparable; thus, a Orlistat course can alleviate diabetes and atherosclerosis. According to a number of clinical studies, Orlistat acts exclusively on enzymes, affecting no other organs of the body. The drug is not absorbed into the bloodstream and causes no intoxication. Since the body no longer accumulates fat, it uses hypodermic reserves leaving the muscle tissues unchanged at the same. Slimming process occurs as a result of burning fat. Therefore, even a long-term Orlistat course will hardly cause harm to an organism. In conjunction with diet and exercises the medication can prevent repeated weight gain. Since Orlistat doesn’t interfere with other medications, it can be administered in combination with virtually any drug type.
Orlistat indications for use
The preparation is characterized by narrow scope of action and typically prescribed in the following cases:
1. Prolonged therapy with obese patients or overweight patients, including those associated with obesity risk factors, combined with moderate calorie diet.
2. Obesity treatment combined with hypoglycemic agents (metformin, sulfonylureas and/or insulin) or moderately hypocaloric diet in patients with type 2 diabetes.
Orlistat is effective in terms of long-term control of body weight (weight loss and maintain it at a new level, preventing re-weight gain). Treatment results in improvement risk factors profile in terms of diseases associated with obesity, including hypercholesterolemia, Type 2 diabetes mellitus, impaired glucose tolerance, hyperinsulinemia, hypertension; the remedy decreases the amount of visceral fat.
One capsule of Orlistat contains 120mg of active ingredient. Each capsule is taken after meals; for effective results, it is necessary to properly distribute the daily food intakes, as well as the content of protein, fat and carbohydrates. Taking the drug Orlistat may result into weight loss by 20% approximately. If the body has an overabundance of fat, the weight loss rate may be increased to up to 30%.
Please, start the course only once you’ve consulted your treating doctor. Notify your doctor of any allergic reactions to medications. The doctor or pharmacist should be aware of your health problems, especially if you have problems such as digestive problems (chronic malabsorption syndrome) or gallbladder (cholestasis), kidney stones/other issues (e.g., calcium oxalate kidney stones, hyperoxaluria), underactive thyroid (hypothyroidism), on certain eating disorders (anorexia nervosa / bulimia).